农场动物成像的各种应用基于某些身体部位的重量和从动物的CT图像切割的估计。在许多情况下，由于扫描非镇静的活动物，通过CT图像中的姿势的巨大变化来增加问题的复杂性。在本文中，我们提出了一种估计来自（可能）活体动物的CT图像的切割和身体部位的重量的一般和鲁棒方法。我们通过弹性登记和联合功能和用于斗篷的回归分量的模型选择，适应基于多标准的分段以及具有大量特征和较少量的样本。通过兔育种程序中的真实应用来评估和说明所提出的技术，显示R ^ 2比以前的技术和方法高于以前的技术和方法。所提出的技术很容易适应类似的问题，因此，它在开源软件包中共享，以便为社区的利益。

Dyadic and small group collaboration is an evolutionary advantageous behaviour and the need for such collaboration is a regular occurrence in day to day life. In this paper we estimate the perceived personality traits of individuals in dyadic and small groups over thin-slices of interaction on four multimodal datasets. We find that our transformer based predictive model performs similarly to human annotators tasked with predicting the perceived big-five personality traits of participants. Using this model we analyse the estimated perceived personality traits of individuals performing tasks in small groups and dyads. Permutation analysis shows that in the case of small groups undergoing collaborative tasks, the perceived personality of group members clusters, this is also observed for dyads in a collaborative problem solving task, but not in dyads under non-collaborative task settings. Additionally, we find that the group level average perceived personality traits provide a better predictor of group performance than the group level average self-reported personality traits.

To apply federated learning to drug discovery we developed a novel platform in the context of European Innovative Medicines Initiative (IMI) project MELLODDY (grant n{\deg}831472), which was comprised of 10 pharmaceutical companies, academic research labs, large industrial companies and startups. The MELLODDY platform was the first industry-scale platform to enable the creation of a global federated model for drug discovery without sharing the confidential data sets of the individual partners. The federated model was trained on the platform by aggregating the gradients of all contributing partners in a cryptographic, secure way following each training iteration. The platform was deployed on an Amazon Web Services (AWS) multi-account architecture running Kubernetes clusters in private subnets. Organisationally, the roles of the different partners were codified as different rights and permissions on the platform and administrated in a decentralized way. The MELLODDY platform generated new scientific discoveries which are described in a companion paper.

The Laboratory Automation Plug & Play (LAPP) framework is an over-arching reference architecture concept for the integration of robots in life science laboratories. The plug & play nature lies in the fact that manual configuration is not required, including the teaching of the robots. In this paper a digital twin (DT) based concept is proposed that outlines the types of information that have to be provided for each relevant component of the system. In particular, for the devices interfacing with the robot, the robot positions have to be defined beforehand in a device-attached coordinate system (CS) by the vendor. This CS has to be detectable by the vision system of the robot by means of optical markers placed on the front side of the device. With that, the robot is capable of tending the machine by performing the pick-and-place type transportation of standard sample carriers. This basic use case is the primary scope of the LAPP-DT framework. The hardware scope is limited to simple benchtop and mobile manipulators with parallel grippers at this stage. This paper first provides an overview of relevant literature and state-of-the-art solutions, after which it outlines the framework on the conceptual level, followed by the specification of the relevant DT parameters for the robot, for the devices and for the facility. Finally, appropriate technologies and strategies are identified for the implementation.

增加制药实验室和生产设施的自动化水平起着至关重要的作用。然而，这一领域的特殊要求使其挑战适应其他行业中存在的尖端技术。本文概述了相关方法以及如何在制药行业中使用，特别是在发展实验室中。最近的进步包括能够处理能够处理复杂任务的灵活移动机械手。然而，由于接口的多样性，将来自许多不同供应商的设备集成到端到端的自动化系统中是复杂的。因此，在本文中考虑了各种标准化方法，提出了一种概念来进一步服用一步。该概念使具有视觉系统的移动操纵器能够“学习”每个设备的姿势，并利用来自通用云数据库的条形码 - 获取接口信息。该信息包括控制和通信协议定义以及操作设备所需的机器人操作的表示。为了定义与设备相关的动作，设备必须具有 - 除了条形码 - 作为标准的基准标记。在随访论文中的适当研究活动之后，将详细阐述该概念。